diff --git a/packages/svelte/src/internal/client/dom/template.js b/packages/svelte/src/internal/client/dom/template.js
index 9e68e7867f..fca13e208e 100644
--- a/packages/svelte/src/internal/client/dom/template.js
+++ b/packages/svelte/src/internal/client/dom/template.js
@@ -15,7 +15,7 @@ import {
 	TEMPLATE_USE_MATHML,
 	TEMPLATE_USE_SVG
 } from '../../../constants.js';
-import { current_renderer } from '../custom-renderer/state.js';
+import { current_renderer, parent_renderer } from '../custom-renderer/state.js';
 import { active_effect } from '../runtime.js';
 import { hydrate_next, hydrate_node, hydrating, set_hydrate_node } from './hydration.js';
 import {
@@ -50,10 +50,36 @@ const SCRIPT_TAG = IS_XHTML ? 'script' : 'SCRIPT';
 export function assign_nodes(start, end) {
 	var effect = /** @type {Effect} */ (active_effect);
 	if (effect.nodes === null) {
-		effect.nodes = { start, end, a: null, t: null };
+		effect.nodes = {
+			start,
+			end,
+			segments: should_segment_nodes(effect)
+				? [{ start, end, r: current_renderer, pr: parent_renderer }]
+				: null,
+			a: null,
+			t: null
+		};
+	} else if (should_segment_nodes(effect)) {
+		var nodes = effect.nodes;
+		(nodes.segments ??= [{ start: nodes.start, end: nodes.end, r: effect.r, pr: effect.pr }]).push({
+			start,
+			end,
+			r: current_renderer,
+			pr: parent_renderer
+		});
 	}
 }
 
+/**
+ * @param {Effect} effect
+ */
+function should_segment_nodes(effect) {
+	return (
+		(current_renderer !== effect.r || parent_renderer !== effect.pr) &&
+		(current_renderer?.foreign != null || parent_renderer?.foreign != null)
+	);
+}
+
 /**
  * @param {string} content
  * @param {number} flags
@@ -386,6 +412,12 @@ export function append(anchor, dom) {
 		// of the parent component. Check for defined for that reason to avoid rewinding the parent's end marker.
 		if ((effect.f & REACTION_RAN) === 0 || effect.nodes.end === null) {
 			effect.nodes.end = hydrate_node;
+
+			// this is to cover interleaved custom renders where an hydrated dom component interleaves with a custom renderer
+			// since it will use segments instead of start/end, we need to make sure to update the segment's end as well
+			if (effect.nodes.segments !== null) {
+				effect.nodes.segments[0].end = hydrate_node;
+			}
 		}
 
 		hydrate_next();
diff --git a/packages/svelte/src/internal/client/reactivity/effects.js b/packages/svelte/src/internal/client/reactivity/effects.js
index b6cb56a866..ad2fb4ce27 100644
--- a/packages/svelte/src/internal/client/reactivity/effects.js
+++ b/packages/svelte/src/internal/client/reactivity/effects.js
@@ -521,7 +521,7 @@ export function destroy_effect(effect, remove_dom = true) {
 		effect.nodes !== null &&
 		effect.nodes.end !== null
 	) {
-		remove_effect_dom(effect.nodes.start, /** @type {TemplateNode} */ (effect.nodes.end));
+		remove_effect_nodes(effect);
 		removed = true;
 	}
 
@@ -586,6 +586,26 @@ export function remove_effect_dom(node, end) {
 	}
 }
 
+/**
+ * @param {Effect} effect
+ */
+function remove_effect_nodes(effect) {
+	var nodes = /** @type {NonNullable<Effect['nodes']>} */ (effect.nodes);
+	var segments = nodes.segments;
+
+	if (segments === null) {
+		remove_effect_dom(nodes.start, /** @type {TemplateNode} */ (nodes.end));
+		return;
+	}
+
+	for (var i = segments.length - 1; i >= 0; i--) {
+		var segment = segments[i];
+		var pop_renderer = push_renderer(segment.r, segment.pr);
+		remove_effect_dom(segment.start, /** @type {TemplateNode} */ (segment.end));
+		pop_renderer?.();
+	}
+}
+
 /**
  * Detach an effect from the effect tree, freeing up memory and
  * reducing the amount of work that happens on subsequent traversals
diff --git a/packages/svelte/src/internal/client/reactivity/types.d.ts b/packages/svelte/src/internal/client/reactivity/types.d.ts
index ecae5f1d36..8b5be77af2 100644
--- a/packages/svelte/src/internal/client/reactivity/types.d.ts
+++ b/packages/svelte/src/internal/client/reactivity/types.d.ts
@@ -65,12 +65,21 @@ export interface Derived<V = unknown> extends Value<V>, Reaction {
 export interface EffectNodes {
 	start: TemplateNode;
 	end: TemplateNode | null;
+	/** Renderer-local ranges, used when a component interleaves custom and foreign-rendered nodes */
+	segments: null | EffectNodeSegment[];
 	/** $.animation */
 	a: AnimationManager | null;
 	/** $.transition */
 	t: TransitionManager[] | null;
 }
 
+export interface EffectNodeSegment {
+	start: TemplateNode;
+	end: TemplateNode | null;
+	r: Renderer | null;
+	pr: Renderer | null;
+}
+
 export interface Effect extends Reaction {
 	/**
 	 * Branch effects store their start/end nodes so that they can be